Aminotrofic Studies

Preclinical studies

Morphometric Changes Induced by Amino Acid Supplementation
in Skeletal and Cardiac Muscles of Old Mice

Giovanni Corsetti, PhD, Evasio Pasini, MD, Giuseppe D’Antona, MD, PhD, Enzo Nisoli, MD, PhD,Vincenzo Flati, PhD, Deodato Assanelli, MD, Francesco S. Dioguardi, MD, and Rossella Bianchi, MD, PhD

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis inMiddle-Aged Mice

Giuseppe D’Antona, Maurizio Ragni, Annalisa Cardile, Laura Tedesco, Marta Dossena, Flavia Bruttini, Francesca Caliaro, Giovanni Corsetti, Roberto Bottinelli, Michele O. Carruba, Alessandra Valerio,
and Enzo Nisoli

Rehabilitation in Sarcopenic Elderly

Essential Amino Acids and Exercise Tolerance in Elderly Muscle-Depleted Subjects with Chronic Diseases: A Rehabilitation without Rehabilitation?

Roberto Aquilani, Giuseppe D’Antona, Paola Baiardi, Arianna Gambino, Paolo Iadarola, Simona Viglio, Evasio Pasini, Manuela Verri, Annalisa Barbieri, and Federica Boschi

Medicina generale vs. scompenso cardiaco cronico e bronco pneumopatia cronica ostruttiva: possibilità di conseguire risultati riabilitativi senza la riabilitazione

Roberto Aquilani, Federica Boschi

From mitochondria to healthy aging: The role of branched-chain amino acids treatment: MATeR a randomized study

Ilaria Buondonno, Francesca Sassi, Giulia Carignano, Francesca Dutto,
Cinzia Ferreri, Fausto G. Pili, Massimiliano Massaia, Enzo Nisoli, Chiara Ruocco,
Paola Porrino, Claudia Ravetta, Chiara Riganti, Giovanni C. Isaia, Patrizia D’Amelio

Myostatin as a potential biomarker to monitor sarcopenia in hip fracture patients undergoing a multidisciplinary rehabilitation and nutritional treatment: a preliminary study

Alessandro de Sire, Alessio Baricich,
Filippo Renò, Carlo Cisari, Nicola Fusco
& Marco Invernizzi

Effects of essential amino acid supplementation and rehabilitation on functioning in hip fracture patients: a pilot randomized controlled trial

Marco Invernizzi, Alessandro de Sire, Federico D’Andrea, Deborah Carrera, Filippo Renò, Silvia Migliaccio, Giovanni Iolascon, Carlo Cisari

Effect of essential amino acid supplementation on quality of life, Amino acid profile and strength in institutionalized elderly patients

Mariangela Rondanelli, Annalisa Opizzi, Neldo Antoniello, Federica Boschi, Paolo Iadarola, Evasio Pasini, RobertoAquilani, Francesco Saverio Dioguardi

Nutritional Supplements with Oral Amino Acid Mixtures Increases Whole-Body Lean Mass and Insulin Sensitivity in Elderly Subjects with Sarcopenia

Sebastiano B. Solerte, MD, PhD, Carmine Gazzaruso, MD, Roberto Bonacasa, MD,
Mariangela Rondanelli, MD, Mauro Zamboni, MD, Cristina Basso, MD, PhD,
Eleonora Locatelli, MD, Nicola Schifino, MD, Andrea Giustina, MD, PhD, and
Marisa Fioravanti, BS

Decreased Incidence of Infections

Effects of oral amino acid supplementation on long-term-care-acquired infections in elderly patients

Roberto Aquilani, Ginetto Carlo Zuccarelli, Francesco Saverio Dioguardi, Paola Baiardi, Antonio Frustaglia, Carla Rutili, Elena Comi, Michele Catani, Paolo Iadarola,
Simona Viglio, Annalisa Barbieri, Luca D’Agostino, Manuela Verri,
Evasio Pasini, Federica Boschi

Supplementation of Essential Amino Acids May Reduce the Occurrence of Infections in Rehabilitation Patients With Brain Injury

Mirella Boselli, Roberto Aquilani, Paola Baiardi, Francesco Saverio Dioguardi, Caterina Guarnaschelli, Maria Pia Achilli, Nadia Arrigoni, Paolo Iadarola, Manuela Verri, Simona Viglio, Annalisa Barbieri and Federica Boschi

Essential amino acid supplementation is associated with reduced serum C-reactive protein levels and improved circulating lymphocytes in post-acute inflamed elderly patients

Roberto Aquilani, Ginetto C. Zuccarelli, Roberto Maestri, Mirella Boselli, Maurizia Dossena, Eleonora Baldissarro, Federica Boschi, Daniela Buonocore and Manuela Verri

Management of Dysphagia in Stroke Patients

Unaffected Arm Muscle Hypercatabolism in Dysphagic
Subacute Stroke Patients: The Effects of Essential Amino
Acid Supplementation

Roberto Aquilani, Mirella Boselli, Giuseppe D’Antona, Paola Baiardi,
Federica Boschi, Simona Viglio, Paolo Iadarola, Evasio Pasini, Annalisa Barbieri, Maurizia Dossena, Andria Innocenza Bongiorno, and Manuela Verri

CHF

Adequate energy-protein intake is not enough to improve nutritional and metabolic status in muscle-depleted patients with chronic heart failure

Roberto Aquilani, Cristina Opasich, Alessandra Gualco, Manuela Verri, Amidio Testa, Evasio Pasini, Simona Viglio, Paolo Iadarola, Ornella Pastoris, Maurizia Dossena, Federica Boschi

Oral Amino Acid Supplements Improve Exercise Capacities in
Elderly Patients with Chronic Heart Failure

Roberto Aquilani, MD, Simona Viglio, PhD, Paolo Iadarola, PhD, Cristina Opasich, MD, Amidio Testa, MD, Francesco S. Dioguardi, MD, and Evasio Pasini, MD

The role of nutritional supplementation with essential amino acids in patients with chronic heart failure

A. Macchi, I. Franzoni, F. Buzzetti, M. C. Pedrigi, I. Rosa, G. V. Gaudio, A. Margonato

Impairment in Walking Capacity and Myocardial Function in the Elderly: Is There a Role for Nonpharmacologic Therapy with Nutritional Amino Acid Supplements?

Roldano Scognamiglio, MD, Amidio Testa, MD, Roberto Aquilani, MD,
Francesco S. Dioguardi, MD, and Evasio Pasini, MD

Effects of Oral Amino Acid Supplements on Cardiac Function
and Remodeling in Patients with Type 2 Diabetes with Mild-to-Moderate Left Ventricular Dysfunction

Roldano Scognamiglio, MD, Christian Negut, MD, Monica Palisi, MD,
Francesco S. Dioguardi, MD, Micol Coccato, MD, and Sabino Iliceto, MD

COPD

Fat-free mass change after nutritional rehabilitation in weight losing COPD: role of insulin, C-reactive protein and tissue hypoxia

Simonetta Baldi, Roberto Aquilani, Gian Domenico Pinna, Paolo Poggi, Angelo De Martini, Claudio Bruschi

Effetti di un intervento di supplementazione nutrizionale
nella riabilitazione di pazienti bpco con sarcopenia: studio ongoing

Elena Venturelli, Cristina Lorenzi, Matilde Ghidoni, Nicoletta Kidonias, Lucia Bortolotti, Rita Iattoni,Daniela Lugli, Sasha Lucic,
Francesco Prato, Nicoletta Ara

Effetti di un intervento di supplementazione nutrizionale
nella riabilitazione di pazienti bpco con sarcopenia: studio ongoing

Elena Venturelli, Cristina Lorenzi, Matilde Ghidoni, Nicoletta Kidonias, Lucia Bortolotti, Rita Iattoni,Daniela Lugli, Sasha Lucic,
Francesco Prato, Nicoletta Ara

Hemodialysis

A Novel Amino Acids Oral Supplementation in Hemodialysis Patients a Pilot Sudy

Piergiorgio Bolasco, Stefania Caria, Adamasco Cupisti, Romina Secci and Francesco Saverio Dioguardi

Differences in Amino Acid Loss Between High-Efficiency Hemodialysis and Postdilution and Predilution Hemodiafiltration Using High Convection Volume Exchange—A New Metabolic Scenario? A Pilot Study

Stefano Murtas, MD, Roberto Aquilani, MD, Maria Luisa Deiana, MD, Paolo Iadarola, PhD, Romina Secci, RN, Mariella Cadeddu, RN, Stefano Salis, RN, Doriana Serpi, RN, and Piergiorgio Bolasco, MD

Effects of a new mixture of essential amino acids (Aminotrofic) in malnourished haemodialysis patients

S. G. Sukkar, F. Gallo, C. Borrini, A. Vaccaro, C. Marchello, R. Boicelli, C. Borgarelli, P. Solari, C. E. Ratto, G. Ravera

Diabetes

Improvement of Blood Glucose Control and Insulin Sensitivity
During a Long-Term (60 Weeks) Randomized Study with Amino Acid Dietary Supplements in Elderly Subjects with Type 2 Diabetes Mellitus

Sebastiano B. Solerte, MD, PhD, Marisa Fioravanti, BS, Eleonora Locatelli, MD,
Roberto Bonacasa, MD, Mauro Zamboni, MD, Cristina Basso, MD, PhD,
Anna Mazzoleni, MD, Valeria Mansi, MD, Nikolas Geroutis, MD,
and Carmine Gazzaruso, MD

Oncology

INTEGRAZIONE ALIMENTARE CON AMINOTROFIC
NEL PAZIENTE ONCOLOGICO IN AREA TERAPEUTICA.
STUDIO PROSPETTICO RANDOMIZZATO
IN DOPPIO CIECO

F. D’Andrea, M. Serioli, S. Riso

Open phase II study on efficacy and safety of an oral amino acid functional cluster supplementation in cancer cachexia

Clelia Madeddu, Antonio Macciò, Giorgio Astara, Elena Massa, Mariele Dessì, Giorgia Antoni, Filomena Panzone, Roberto Serpe, Giovanni Mantovani

Parkinson

Amino acid supplementation in L-dopa treated Parkinson’s disease patients

A. Cucca, S. Mazzucco, A. Bursomanno, L. Antonutti, F.G. Di Girolamo, G. Pizzolato,
N. Koscica, G.L. Gigli, M. Catalan, G. Biolo

HIV

Effects of an amino acid formula administered orally to malnourished HIV-positive patients: short-term results

Paola Manfrin, Consuelo Vecchio, Davide Minisci, Fulvio Muzio

Pharmacoeconomics

Costo delle infezioni in una residenza sanitaria assistenziale.
Analisi del costo/efficacia della supplementazione con amino acidi

Roberto Aquilani, Roberto Aquilani, Ginetto C. Zuccarelli, Evasio Pasini, Federica Boschi

Kinetics

Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components

Mariangela Rondanelli, Roberto Aquilani, Manuela Verri, Federica Boschi, Evasio Pasini, Simone Perna, Anna Faliva & Anna Maria Condino